Archive

Author: Tarannum Syed, University of TorontoReviewer: Hubert Tsui, BSc, MD, PhD, FRCPC, Department of Laboratory Medicine & Pathobiology - Hematological Pathology, Sunnybrook Health Science CentreList the clinical manifestations of polycythemia vera Describe the morphological features of polycythemia vera on a bone marrow biopsy. Explain...

Author: Dr. Ali EshaghpourReviewer: Dr. Rick Ikesaka Objectives: At the end of the self-assessment module, participants will be able to:1. Describe the first-line management of patients with ITP without bleeding. 2. Describe the first-line management of patients with ITP with bleeding. 3. Explain the rationale for the sequencing of...

Author(s): Marissa Laureano1,3, Akash Gupta2,3, Celina Montemayor3, Yulia Lin2Department of Medicine, McMaster University, Hamilton, ON, Canada Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Canadian Blood Services, Toronto, ON, CanadaObjectives: As the end of this self-assessment module, participants should be able...

Author: Dr. Brittany Margaret-Anne SalterReviewer: Dr. Alejandro Garcia-Horton, Assistant Professor (Oncology), McMaster University Objectives At the end of the self-assessment module, participants will be able to:Describe the mechanism of anemia in patients with lower-risk myelodysplastic syndrome (LR-MDS). Explain the diagnostic criteria for MDS with ring sideroblasts Describe...

Author: Dr. Joanne Britto, McMaster University Reviewer: Dr. Amaris Balitsky, Assistant Professor, Department of Oncology, McMaster Objectives At the end of the self-assessment module, participants will be able to:1. Describe the available treatment options to improve post-autologous stem cell transplantation outcomes for patients with Hodgkin lymphoma. 2. Describe the...

Author: Dr. Yan Xu, University of Ottawa Reviewer: Dr. Johnathan Mack, University of Ottawa Objectives At the end of the self-assessment module, participants will be able to:1. Describe the epidemiology and risk factors associated with fetal and neonatal thrombocytopenia (FNAIT) 2. Develop an approach to secondary prophylaxis among mothers...

Author: Dr. Joanne Britto, McMaster University. Reviewer: Dr. Menaka Pai, Associate Professor, Division of Hematology & Thromboembolism, Department of Medicine, McMaster University Objectives At the end of the self-assessment module, participants will be able to: 1. Identify the clinical manifestations of acute hepatic porphyria (AHP) 2. Describe the pathophysiology of...

NEJM: https://www.nejm.org/doi/full/10.1056/NEJMoa2004444Author: Dr. Danyal Ladha, University of Ottawa Reviewer: Dr. Hassan Sibai, University of Toronto Objectives At the end of the self-assessment module, participants will be able to: 1. Describe the role of maintenance therapy in the post-remission management of AML 2. Define the mechanism of action and clinical efficacy...

Author: Dr. Danyal Ladha, University of Ottawa Reviewer: Dr. Michael Kennah, Transplant and Cellular Therapy Program, University of Ottawa Objectives At the end of the self-assessment module, participants will be able to:1. Describe the approved indications for CAR T-cell therapy in Canada. 2. Describe the adverse events associated with...